Kaur, Balwinder and Srivastava, Rajendra and Satpat, Biswarup and Kondepudi, Kanthi Kiran and Bishnoi, Mahendra (2015) Biomineralization of hydroxyapatite in silver ion-exchanged nanocrystalline ZSM-5 zeolite using simulated body fluid. Colloids and Surfaces B: Biointerfaces, 135. pp. 201-208. ISSN 0927-7765

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Abstract

Silver ion-exchanged nanocrystalline zeolite (Ag-Nano-ZSM-5) and silver ion-exchanged conventional zeolite (Ag-ZSM-5) were synthesized. Zeolites were incubated in simulated body fluid at 310 K for different time periods to grow hydroxyapatite in their matrixes. Significant large amount of hydroxyapatite was grown in Ag-Nano-ZSM-5 matrix after incubation in simulated body fluid when compared to Ag-ZSM-5. The resultant material was characterized using X-ray diffraction, N2-adsorption, scanning/transmission electron microscopy, energy dispersive X-ray, and inductively coupled plasma analysis. Mechanical properties such as compressive modulus, compressive strength, and strain at failure of the parent materials were evaluated. Biocompatibility assays suggested that Ag-Nano-ZSM-5 and hydroxyapatite grown in Ag-Nano-ZSM-5 were compatible and did not impose any toxicity to RAW 264.7 cells macrophase and Caco2 cells suggesting considerable potential for biomedical applications such as bone implants.

Item Type:	Article
Uncontrolled Keywords:	Nanocrystalline zeolite; Hydroxyapatite; Bio nanocomposite; Simulated body fluid; Bioactivity
Subjects:	Food Science and Technology Nutrition Science and Technology
Depositing User:	Dr. Author @NABI
Date Deposited:	05 Aug 2016 04:58
Last Modified:	05 Aug 2016 04:58
URI:	http://nabi.sciencecentral.in/id/eprint/36

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